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Updated: May 18, 2026

In Situ Detection and Single Cell Quantification of Metal Oxide Nanoparticles Using Nuclear Microprobe Analysis
Published on: February 3, 2018
Historical overview of nanotechnology and nanotoxicology
1Center for Toxicology and Mechanistic Biology, Exponent®, Inc, Houston, TX, USA. asantamaria@exponent.com
Abstract:
Although scientists have been studying nanoscience phenomena for many decades, technological developments in the second half of the twentieth century provided valuable tools that permitted researchers to study and develop materials in the nanoscale size range and helped formalize nanotechnology as a scientific field. This chapter provides a brief history of the field of nanotechnology, with an emphasis on the development of nanotoxicology as a scientific field. A brief overview of the worldwide regulatory activities for nanomaterials is also presented. The future development and safe use of nanomaterials in a diverse range of consumer products will be interesting, intellectually challenging, exciting, and hopefully very beneficial for the society.
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