Capillary electrophoresis for the detection of Fragile X expanded alleles
Rong Mao1, Pinar Bayrak-Toydemir, Elaine Lyon
1Pathology Department, University of Utah School of Medicine, Salt Lake City, UT, USA. rong.mao@aruplab.com
Methods in Molecular Biology (Clifton, N.J.)
|September 15, 2012
Abstract:
Capillary electrophoresis is an analytical technique that separates ions based on their electrophoresis mobility with the use of an applied voltage. Capillary electrophoresis is used most predominantly in nuclear acid fragment analysis as well as DNA sequencing because it gives faster results and provides high resolution separation. Here we describe an application using capillary electrophoreses for screening the Fragile X expanded alleles to demonstrate the application.
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