A modified side-to-end lymphaticovenular anastomosis
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Updated: May 18, 2026

Re-Arterialized Rat Partial Liver Transplantation with an in vivo Vessel-Oriented 70% Hepatectomy
Published on: April 8, 2018
Takumi Yamamoto1, Hidehiko Yoshimatsu, Mitsunaga Narushima
1Department of Plastic and Reconstructive Surgery, Graduate School of Medicine, The University of Tokyo, Bunkyo-ku, Tokyo, Japan. tyamamoto-tky@umin.ac.jp
Background:
Lymphaticovenular anastomosis (LVA) is a useful treatment for compression-refractory lymphedema with its effectiveness and minimal invasiveness. However, LVA requires supermicrosurgery, where lymphatic vessels with a diameter of 0.5 mm or smaller are anastomosed using 11-0 or 12-0 suture. To make LVA easier and safer, we adopted a modified side-to-end (S-E) anastomosis in LVA surgery.
Methods:
We performed modified S-E LVAs in 14 limbs of female patients with lower extremity lymphedema (LEL). In modified S-E LVA, lateral windows with a length of 1.0 mm or longer were created on a lymphatic vessel and a vein, respectively, and side-to-side (S-S) anastomosis was established with 10-0 continuous suture. After completion of S-S anastomosis, the vein distal to the anastomosis site was ligated to prevent venous backflow and subsequent thrombosis at the anastomosis site. Lymphedematous volume was evaluated preoperatively and at postoperative 6 months using LEL index.
Results:
All the 24 modified S-E anastomoses could be completed without difficulty or revision for anastomosis, and showed good patency after completion of anastomosis. Postoperatively, LEL indices significantly decreased compared with preoperative LEL index (255.9 ± 14.1 vs. 274.9 ± 22.2, P < 0.001).
Conclusions:
Modified S-E LVA can efficaciously divert lymph flows into venous circulation without performing supermicrosurgical anastomosis.
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