Related Experiment Video
Updated: May 18, 2026

A Melanoma Patient-Derived Xenograft Model
Published on: May 20, 2019
Facial resurfacing with a monoblock full-thickness skin graft after multiple malignant melanomas excision in
Selahattin Ozmen1, Safak Uygur, Tolga Eryilmaz
1Gazi University Faculty of Medicine, Department of Plastic, Reconstructive and Aesthetic Surgery, Ankara, Turkey.
Abstract:
Xeroderma pigmentosum is an autosomal recessive disease, characterized by vulnerability of the skin to solar radiation. Increase in sunlight-induced cancer is a direct consequence of an increase in mutated cells of the skin of patients with xeroderma pigmentosum. There is no specific technique for facial resurfacing in patients with xeroderma pigmentosum. In this article, a patient with xeroderma pigmentosum with multiple malignant melanomas on her face and radical excision of total facial skin followed by facial resurfacing with monoblock full-thickness skin graft from the abdomen is presented.
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