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Shoulder Joint Infectious Arthritis and Acromioclavicular Joint Osteomyelitis due to Candida
Kil-Byung Lim1, Yee-Gyung Kwak, Young-Sup Kim
1Department of Rehabilitation Medicine, Inje University, College of Medicine, Ilsan Paik Hospital, Goyang 411-706, Korea.
Abstract:
Candida species inhabit the skin and mucous membranes of healthy individuals with low virulence, and osteomyelitis due to candida is very rare. However, the incidence of invasive candidal infection caused by intravenous drug use, broad-spectrum antibiotics, and indwelling central venous catheter is increasing. A 73-year old man visited the outpatient clinic complaining of right shoulder pain that radiated to the right acromioclavicular joint. He had undergone multiple injection procedures followed by nonsteroidal anti-inflammatory drug therapy for several weeks. The ultrasonographic findings showed a heterogeneous mass around the right acromioclavicular joint, while the right shoulder MRI and the overall findings of the body bone scan were suggestive of osteomyelitis. Pathologic findings of ultrasonographically guided joint aspiration fluid showed acute and chronic nonspecific inflammation, while the tissue culture and staining revealed Candida parapsilosis.
Insights
A rare case of Candida parapsilosis osteomyelitis in the shoulder is presented. This fungal infection, often linked to medical devices or drug use, highlights the importance of considering fungi in bone infections.
Area of Science:
- Infectious Diseases
- Mycology
- Orthopedics
Background:
- Candida species are typically commensal organisms with low virulence.
- Invasive candidal infections are increasing due to factors like intravenous drug use and central venous catheters.
- Osteomyelitis caused by Candida species is exceptionally rare.
Purpose of the Study:
- To report a rare case of Candida parapsilosis osteomyelitis.
- To discuss the diagnostic challenges and clinical presentation of fungal osteomyelitis.
- To emphasize the importance of considering fungal pathogens in specific patient populations.
Main Methods:
- Clinical presentation of a 73-year-old man with right shoulder pain.
- Diagnostic imaging including ultrasonography, MRI, and bone scan.
- Ultrasonographically guided joint aspiration for fluid analysis, culture, and staining.
Main Results:
- Imaging suggested osteomyelitis of the right acromioclavicular joint.
- Pathologic findings revealed acute and chronic inflammation.
- Tissue culture and staining identified Candida parapsilosis as the causative agent.
Conclusions:
- Candida parapsilosis can cause rare but serious bone infections.
- Early and accurate diagnosis is crucial for effective treatment of fungal osteomyelitis.
- Clinical suspicion should be raised in patients with risk factors for invasive fungal infections.
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