Search research articles

Search research articles

Related Experiment Videos

Injection rate: a factor in contrast reactions?

M J Duddy¹, R A Manns, S A Wormald

¹Department of Radiology, Queen Elizabeth Hospital, Edgbaston, Birmingham.

Clinical Radiology

|January 1, 1990

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Infrainguinal Vein Graft Stenoses: Long-Term Outcomes of Graft Angioplasty.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2016

Same author

Cranial ultrasound for the diagnosis of giant cell arteritis. A retrospective cohort study.

The journal of the Royal College of Physicians of Edinburgh·2016

Same author

Stenting as a bail-out option after failed percutaneous transluminal angioplasty in infrainguinal vein bypass grafts.

Vascular·2015

Same author

Below-the-ankle angioplasty is a feasible and effective intervention for critical leg ischaemia.

European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery·2010

Same author

The radiological reporting of lumbar Scheuermann's disease: an unnecessary source of confusion amongst clinicians and patients.

The British journal of radiology·2008

Same author

Hypothenar hammer syndrome in a patient with rheumatoid arthritis: a mimic of vasculitis.

Rheumatology (Oxford, England)·2006

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

This study found no significant difference in contrast reaction frequency between slow and rapid injection rates for excretion urography. The rate of contrast media administration did not impact patient adverse events.

Area of Science:

Radiology
Medical Imaging
Pharmacology

Background:

Iodinated contrast media are essential for diagnostic imaging procedures like excretion urography.
Patient safety is paramount, and understanding factors influencing adverse reactions is crucial.
The rate of contrast injection may influence the incidence and severity of reactions.

Purpose of the Study:

To compare the frequency of contrast reactions in patients undergoing excretion urography based on the rate of contrast medium injection.
To determine if a faster injection rate of meglumine diatriazoate and sodium diatriazoate mixture is associated with a higher or lower incidence of adverse events.

Main Methods:

A prospective, randomized study involving 100 patients undergoing excretion urography.
Patients were assigned to either a slow (mean 0.975 ml/s) or rapid (mean 2.575 ml/s) injection group using Urografin 325 (a mixture of meglumine diatriazoate and sodium diatriazoate).

Related Experiment Videos

The incidence of significant contrast reactions was recorded and compared between the two groups.

Main Results:

A total of 100 patients were analyzed, with 50 in each injection rate group.
Significant contrast reactions occurred in 6 out of 50 patients (12%) in the slow injection group.
Significant contrast reactions occurred in 4 out of 50 patients (8%) in the rapid injection group.

Conclusions:

There was no statistically significant relationship found between the rate of contrast injection and the occurrence of contrast reactions (P > 0.1).
The findings suggest that injection speed may not be a critical factor in predicting adverse events for this specific contrast agent and procedure.
Further research could explore other patient-specific factors or different contrast agents.