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Related Experiment Video

Updated: May 18, 2026

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Anterior High-Resolution Optical Coherence Tomography in the Diagnosis and Therapeutic Monitoring of Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

Intraocular schwannoma.

Jae Young You¹, Paul T Finger, Codrin Iacob

¹Department of Pathology and Laboratory Medicine, The New York Eye and Ear Infirmary, New York, NY 10003, USA.

Survey of Ophthalmology

|September 18, 2012

Summary

Intraocular schwannomas are rare tumors that can mimic malignant melanoma. This study reviews 46 cases, emphasizing characteristics of uveal schwannoma with extrascleral extension.

Area of Science:

Ophthalmology
Oncology
Pathology

Background:

Schwannomas, tumors of neoplastic Schwann cells, are common in the head and neck but rare in intraocular tissues.
Uveal schwannomas are often misdiagnosed as uveal malignant melanoma due to similar clinical presentations.
Existing literature on intraocular schwannoma primarily consists of limited case reports and reviews.

Observation:

This study presents a case of choroidal schwannoma with extrascleral extension.
A comprehensive review of 46 previously reported uveal schwannoma cases was conducted.
The clinical and pathological features of intraocular schwannomas, particularly those with extrascleral extension, were delineated.

Findings:

Extrascleral extension in uveal schwannoma is an uncommon feature with largely unknown prognostic significance.

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Analysis of clinical and pathological data aimed to characterize intraocular schwannomas and their growth patterns.

The study sought to provide a more comprehensive understanding beyond isolated case reports.

Implications:

Enhanced understanding of uveal schwannoma characteristics, aiding in differential diagnosis from malignant melanoma.
Clarification of the clinical and pathological significance of extrascleral extension in intraocular schwannoma.
Contribution to the limited body of knowledge on rare intraocular tumors, potentially guiding future diagnostic and treatment strategies.