Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: May 18, 2026

Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays

Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays

Published on: May 29, 2017

nSTAT: open-source neural spike train analysis toolbox for Matlab.

I Cajigas¹, W Q Malik, E N Brown

¹Department of Anesthesia and Critical Care, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA. iahn@mit.edu

Journal of Neuroscience Methods

|September 18, 2012

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Corrigendum to 'Role of electroencephalogram oscillations and the spectrogram in monitoring anaesthesia' [BJA Education 20 (2020) 166-172].

BJA education·2021

Same author

Role of electroencephalogram oscillations and the spectrogram in monitoring anaesthesia.

BJA education·2021

Same author

Using EEG markers to make inferences about anaesthetic-induced altered states of arousal.

British journal of anaesthesia·2018

Same author

Electroencephalographic markers of brain development during sevoflurane anaesthesia in children up to 3 years old.

British journal of anaesthesia·2018

Same author

On compression and damage evolution in two thermoplastics.

Proceedings. Mathematical, physical, and engineering sciences·2017

Same author

The Ageing Brain: Age-dependent changes in the electroencephalogram during propofol and sevoflurane general anaesthesia.

British journal of anaesthesia·2015

Same journal

Time as the language of Behavior: events, sequences, patterns and meanings.

Journal of neuroscience methods·2026

Same journal

Detection of cochlear microphonic for differential diagnosis between auditory neuropathy mice and noise-induced sensorineural hearing loss mice.

Journal of neuroscience methods·2026

Same journal

Assessment metrics for pain control in rats: A methodological commentary.

Journal of neuroscience methods·2026

Same journal

Infant EEG preprocessing pipelines: A capability framework and current gaps in practice.

Journal of neuroscience methods·2026

Same journal

Methods for measuring neural activity during voluntary wheel running.

Journal of neuroscience methods·2026

Same journal

Serotype-dependent differences in AAV cellular transduction rates in the hypothalamus of Arctic ground squirrels.

Journal of neuroscience methods·2026

See all related articles

Neuroscientists can now more easily analyze neural data with nSTAT, an open-source MATLAB toolbox. This tool simplifies complex point process generalized linear models (PP-GLMs) for neural decoding and plasticity studies.

Area of Science:

Computational Neuroscience
Systems Neuroscience

Background:

Advances in analytical tools have improved neural function understanding.
Point process generalized linear models (PP-GLMs) are powerful for neural analysis but lack accessible software.

Purpose of the Study:

To develop an open-source software toolbox for MATLAB to enhance the accessibility of PP-GLM methods for neuroscientists.
To provide a user-friendly platform for neural spike train analysis and PP-GLM implementation.

Main Methods:

Developed nSTAT, an object-oriented programming (OOP) toolbox for MATLAB.
Implemented algorithms for peri-stimulus time histograms, neural response properties, and neural plasticity.
Facilitated data manipulation through intuitive object-based operations.

More Related Videos

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Published on: July 26, 2019

Related Experiment Videos

Last Updated: May 18, 2026

Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays

Time-dependent Increase in the Network Response to the Stimulation of Neuronal Cell Cultures on Micro-electrode Arrays

Published on: May 29, 2017

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Using Neuron Spiking Activity to Trigger Closed-Loop Stimuli in Neurophysiological Experiments

Published on: November 12, 2019

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Detecting Pre-Stimulus Source-Level Effects on Object Perception with Magnetoencephalography

Published on: July 26, 2019

Main Results:

nSTAT enables straightforward analysis of neural spike trains and PP-GLM model building.
The toolbox supports exploratory data analysis and stimulus decoding based on neural models.
Offers a platform for modifying and extending PP-GLM techniques for complex neuroscience problems.

Conclusions:

nSTAT democratizes the use of advanced PP-GLM techniques in neuroscience research.
The open-source nature of nSTAT fosters community-driven development and application.
Enhances the ability to model and understand neural function across various research areas.