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A possible genetic component of obesity in childhood. Observations on acid phosphatase polymorphism
N Lucarini1, G Finocchi, F Gloria-Bottini
1Chair of Human Development, 2nd University of Rome School of Medicine, Italy.
Experientia
|January 15, 1990
Abstract:
Phenotypes of acid phosphatase with low enzymatic activity (ACP1 A and BA) are correlated with the highest degree of body mass increase observed in a sample of obese children. Since acid phosphatase probably functions as a flavin-mononucleotide phosphatase, differential modulation of flavo-enzyme activity and energy metabolism due to acid phosphatase genetic variability may explain the observed association.