Related Experiment Video
Updated: May 18, 2026

Spectral Karyotyping to Study Chromosome Abnormalities in Humans and Mice with Polycystic Kidney Disease
Published on: February 3, 2012
Orange-brown chromonychia, a novel finding in Kawasaki disease
Priyankar Pal1, Prabhas Prasun Giri
1Department of Pediatric Rheumatology, Institute of Child Health, Kolkata, West Bengal, India. mailme.priyankar@gmail.com
Abstract:
Kawasaki disease (KD) is one of the commonest vasculitis of childhood, where diagnosis is clinical based on a plethora of signs and symptoms. One of the typical findings is the changes in the extremities including the nail changes. Orange-brown chromonychia is a colour change in the nails which has been observed in some cases of KD. Here, we report a series of 40 patients of KD, where a typical transverse orange-brown discolouration of nails or chromonychia was noted in 29 patients. Though chromonychia is noted in many other rheumatic and nonrheumatic diseases, the typical transverse orange-brown chromonychia observed in KD patients can be included as an additional clinical feature in diagnosis of KD.
Related Concept Videos
Endocarditis II: Clinical Features of Infective Endocarditis
Chronic Kidney Disease II: Clinical Manifestations
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Changes in Skin Color: Clinical Perspectives
Albinism
Albinism is a genetic disorder that affects (completely or partially) the coloring of skin, hair, and eyes. The defect is primarily...
Karyotyping
Myocarditis II: Clinical Features and Diagnostic Tests