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Acetylcholine release in two parts of the canine ileum
E Atanassova1, A Rakovska, K Milenov
1Institute of Physiology, Bulgarian Academy of Sciences, Sofia.
General Pharmacology
|January 1, 1990
Abstract:
1. Electrically-induced contractions and acetylcholine (Ach) release in two parts of the ileum: 5 and 25 cm proximal to the ileo-colic sphincter (ICS) were compared. 2. The amplitude of electrically- and Ach-induced contractions of the ileum 5 cm proximal to the ICS (terminal ileum) was much higher than the amplitude of the contractions of the ileum 25 cm proximal to the ICS. 3. The amount of Ach released in the ileum 25 cm proximal to the ICS accounted for 58% of the amount of Ach released in the terminal ileum, which was taken to be 100%.