Related Experiment Video
Updated: May 18, 2026

Probiotic Studies in Neonatal Mice Using Gavage
Published on: January 27, 2019
Probiotic supplement use among young children in Taiwan: a prospective cohort study
Yi-Chun Chen1, Yi-Wen Chien, Pei-Jen Chang
1School of Nutrition and Health Sciences, Taipei Medical University, Taipei, Taiwan. yichun@tmu.edu.tw
Insights
Probiotic supplement use is common in Taiwanese children, often linked to social advantages and health issues like eczema. Parents may use probiotics for disease prevention or treatment in young children.
Area of Science:
- Pediatrics
- Microbiology
- Public Health
Background:
- Probiotic supplement use in infants and young children is a growing area of interest.
- Understanding factors influencing probiotic use is crucial for public health initiatives.
Purpose of the Study:
- To detail probiotic supplement consumption patterns in young children in Taiwan.
- To identify demographic and health-related factors associated with probiotic use.
Main Methods:
- Utilized data from the Taiwan Birth Cohort Study database.
- Collected information via questionnaires on probiotic use from birth to 18 months.
- Excluded specific infant groups and incomplete responses, analyzing 16,991 valid cases.
Main Results:
- Around 50% of children used probiotics before 18 months; only 6.3% used them consistently.
- Probiotic use was higher in firstborns, children of native mothers, and those from higher socioeconomic backgrounds.
- Breastfed infants, and those with eczema or gastrointestinal issues, showed increased probiotic use.
Conclusions:
- Probiotic use in young children correlates with socioeconomic advantage and specific health conditions.
- Parents may administer probiotics for preventative or therapeutic reasons.
- Findings provide a baseline for future research and inform healthcare professionals on infant probiotic consumption.
Objectives:
The objective of this study is to provide details on probiotic supplement use among young children in Taiwan.
Participants And Methods:
This study is based on the Taiwan Birth Cohort Study database. We used questionnaires to collect information on probiotic supplement use among young children from birth to 18 months of age, while also considering their demographic characteristics and other covariates. Low-birth-weight infants, preterm infants, those with birth defects, and those with caregivers who returned incomplete questionnaires were excluded. The final valid sample comprised 16,991 cases.
Results:
Approximately half the children received probiotic supplements before the age of 18 months. Only 6.3% of the children received probiotic supplements during the two periods of birth to 6 months and 7 to 18 months. Firstborn children, native mothers, mothers with higher educational levels, higher family income, and parents who lead healthy lifestyles were positively related to probiotic supplement use among children. Young children who were breastfed, with eczema, or with gastrointestinal tract problems were significantly positively associated with probiotic supplement use.
Conclusion:
The findings show that probiotic supplement usage among young children is associated with a more socially advantaged circumstance and certain child health factors, such as eczema, diarrhea, and constipation. Parents might use probiotic supplements for prevention or treatment of child diseases. The findings of this research could serve as a baseline for future studies, and provide insight into probiotic supplement use behavior for health professionals caring for infants and young children.
Related Concept Videos
Probiotics
Development of Human Microbiota
Development of the Oral Microbiota
Bioavailability Study Design: Healthy Subjects Versus Patients
Drug Dosing: Infants and Children
Pharmacokinetics in Pediatric Patients: Overview and Drug Absorption

