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Related Experiment Video

Updated: May 18, 2026

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Proton Therapy Delivery and Its Clinical Application in Select Solid Tumor Malignancies

Published on: February 6, 2019

Basics of particle therapy I: physics.

Seo Hyun Park¹, Jin Oh Kang

¹Department of Radiation Oncology, Kyung Hee University School of Medicine, Seoul, Korea.

Radiation Oncology Journal

|September 18, 2012

Summary

Particle therapy, using heavy charged particles, offers theoretical advantages over traditional photon radiation therapy for cancer treatment. This review explores the physics of particle therapy for Korean radiation oncologists.

Keywords:

Carbon ion Neutron Particle therapy Proton

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Published on: March 24, 2022

Area of Science:

Medical Physics
Radiation Oncology
Particle Therapy

Background:

Modern radiation therapy techniques have improved dose conformation and distribution.
Despite advances, improved local control and survival in cancer treatment remain challenging.
Limitations in photon radiation therapy stem from its lower linear energy transfer (LET).

Purpose of the Study:

To review the elementary physics of heavy charged particle therapy.
To highlight the theoretical advantages of particle therapy in radiation oncology.
To inform Korean radiation oncologists about the upcoming heavy charged particle facility.

Main Methods:

Review of fundamental physics principles of particle radiation.
Comparison of physical and biological properties of photons versus heavy charged particles.
Discussion of the Bragg peak phenomenon and its clinical implications.

Main Results:

Heavy charged particles offer superior dose deposition characteristics compared to photons.
Higher Linear Energy Transfer (LET) of heavy charged particles can enhance biological effectiveness.
Particle therapy facilitates precise dose delivery, potentially sparing healthy tissues.

Conclusions:

Particle therapy presents a promising advancement in radiation oncology.
The unique physical and biological properties of heavy charged particles address limitations of photon therapy.
The establishment of a heavy charged particle facility in Korea signifies a commitment to advanced cancer treatment.