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Conjunctival lymphoma arising from reactive lymphoid hyperplasia.
Junichi Fukuhara1, Satoru Kase, Mika Noda
1Department of Ophthalmology, Hokkaido University Graduate School of Medicine, Nishi 7, Kita 15, Kita-ku, Sapporo 060-8638, Japan.
Extra nodal marginal zone B-cell lymphoma (EMZL) of the conjunctiva can arise from reactive lymphoid hyperplasia (RLH). Confirming B-cell clonality via IgH gene rearrangement is crucial for predicting malignancy in conjunctival lesions.
Area of Science:
- Ophthalmology
- Oncology
- Pathology
Background:
- Extra nodal marginal zone B-cell lymphoma (EMZL) of the conjunctiva is rare.
- Its pathogenesis, particularly arising from reactive lymphoid hyperplasia (RLH), is not well understood.
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