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Updated: Jul 21, 2026

Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
A method for evaluating the bronchial circulation. Preliminary observations
C Chiles1, G E Newman, R A Blinder
1Department of Radiology, Duke University Medical Center, Durham, NC 27710.
Abstract:
Due to the small size of the bronchial arteries, the bronchial circulation is difficult to study and remains poorly understood. We have utilized single photon emission computed tomography (SPECT) as a noninvasive means of studying the bronchial circulation. Imaging studies were performed in sheep before and after the introduction of a single pulmonary embolus. Digital bronchial arteriograms demonstrated the dilatation of the bronchial artery which is present on studies one week after embolization. SPECT bronchial perfusion scans reveal a wedge of increased activity that corresponds to a wedge of decreased activity on SPECT pulmonary perfusion images. Axial images available with SPECT provide information about regional alterations of bronchial perfusion not readily apparent on bronchial arteriograms.
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