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Updated: May 18, 2026

Induction of Paralysis and Visual System Injury in Mice by T Cells Specific for Neuromyelitis Optica Autoantigen Aquaporin-4
Published on: August 21, 2017
[Necrotizing autoimmune myopathy]
Levente Bodoki1, Melinda Vincze, Tibor Hortobágyi
1Debreceni Egyetem, Belgyógyászati Klinika, Klinikai Immunológiai Tanszék Debrecen. bodoki.levente@gmail.com
Abstract:
Idiopathic inflammatory myopathies are systemic autoimmune diseases characterized by symmetrical proximal muscle weakness. One of them is the subgroup of necrotizing autoimmune myopathy, which has recently been recognized as a separate entity. In addition to the typical symmetrical muscle weakness, it is characterized by very high creatine kinase levels, myopathic triad in the electromyography, and myocyte necrosis without significant inflammation. The paper aims to review this rare entity, which has to be diagnosed and treated quickly in every case.
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