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Diagnosis of Hirschsprung's Disease by Immunostaining Rectal Suction Biopsies for Calretinin, S100 Protein and Protein Gene Product 9.5
Published on: April 26, 2019
Reoperative surgery for Hirschsprung disease.
Matthew W Ralls1, Arnold G Coran, Daniel H Teitelbaum
1C.S. Mott Children's Hospital, University of Michigan Hospital and Health Systems, Ann Arbor, MI, USA.
Seminars in Pediatric Surgery
|September 19, 2012
Summary
Most children with Hirschsprung disease have successful treatment, but some experience persistent stooling issues. Reoperation may be needed for complications like aganglionosis or enterocolitis.
Area of Science:
- Pediatric surgery
- Gastroenterology
- Clinical outcomes
Background:
- Hirschsprung disease (HSCR) affects the large intestine, causing stooling problems.
- While most children achieve continence after initial surgery, a subset develops persistent issues.
Purpose of the Study:
- To outline diagnostic and surgical strategies for managing persistent stooling issues after initial Hirschsprung disease treatment.
- To address complications requiring reoperation in pediatric patients.
Main Methods:
- Review of diagnostic approaches for persistent stooling issues.
- Description of surgical techniques for redo pull-through procedures.
- Analysis of complications including aganglionosis, enterocolitis, torsion, and stricture.
Main Results:
- Persistent stooling issues are manageable nonoperatively in most cases.
- Reoperation is necessary for a small group of children with specific complications.
- Surgical approach is tailored to the individual complication.
Conclusions:
- Effective management of post-Hirschsprung disease stooling issues requires a tailored diagnostic and surgical approach.
- Addressing complications like aganglionosis, enterocolitis, torsion, and stricture is crucial for successful reoperation.
