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Updated: May 18, 2026

09:53
Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
Published on: July 5, 2021
[Optic neuropathy and meningioma: a diagnostic trap]
M Bouyon1, F Blanc, L Ballonzoli
1Département d'ophtalmologie, hôpitaux universitaires de Strasbourg, 1, place de l'Hôpital, 67091 Strasbourg, France. marie.bouyon@orange.fr
Journal Francais D'Ophtalmologie
|September 19, 2012
Summary
Meningiomas can cause optic neuropathy, delaying diagnosis. Targeted MRI of anterior visual pathways is crucial for identifying these tumors when symptoms are unresponsive to steroids.
Area of Science:
- Neuro-oncology
- Ophthalmology
- Neuroradiology
Background:
- Meningiomas are benign tumors of the meninges.
- Diagnosis can be incidental or symptomatic, often presenting with neurological or ophthalmological issues.
Observation:
- Five women (mean age 52) presented with progressive unilateral vision loss and visual field defects.
- Initial fundus examination was normal, and symptoms mimicked inflammatory central nervous system conditions.
Findings:
- Diagnosis of meningioma was delayed by 18 months to 4 years due to atypical presentation and initial misdiagnosis.
- Optic neuropathy unresponsive to steroids prompted re-evaluation and imaging.
- MRI findings (iso-intense on T1, slightly hyperintense on T2) can be subtle, requiring experienced interpretation.
Implications:
- Consider meningioma of the anterior visual pathways in cases of progressive optic neuropathy unresponsive to steroids.
- Targeted MRI with specific protocols (contrast, fat suppression, anterior pathway focus) is essential for accurate diagnosis and timely management.
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