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Outcomes of open operation for aortoiliac occlusive disease after failed endovascular therapy
Rachel C Danczyk1, Erica L Mitchell, Bryan D Petersen
1Division of Vascular Surgery, Oregon Health & Science University, Portland, OR 97239, USA.
Insights
Patients undergoing secondary open surgery for failed endovascular therapy of aortoiliac occlusive disease (AIOD) had better survival than those with primary open operations. Limb salvage was achieved in all secondary surgery patients.
Area of Science:
- Vascular Surgery
- Cardiovascular Research
- Surgical Outcomes
Background:
- Aortoiliac occlusive disease (AIOD) is a significant vascular condition.
- Endovascular therapy (ET) is a common treatment for AIOD.
- The outcomes of secondary open operations following failed ET are not well-established.
Purpose of the Study:
- To compare patient outcomes of primary open operations for AIOD.
- To compare patient outcomes of secondary open operations for failed ET of AIOD.
Main Methods:
- Retrospective cohort study.
- Analysis of demographic characteristics, comorbidities, and outcomes.
- Inclusion of patients undergoing primary open operation for AIOD or secondary open operation for failed ET of AIOD.
Main Results:
- Mean 5-year survival was 48.2% for primary open surgery vs. 66.8% for secondary open surgery (P = .01).
- All 7 amputations occurred in the primary open surgery group.
- Secondary open surgery patients did not require amputation.
Conclusions:
- Secondary open surgery for failed AIOD ET offers better survival compared to primary open surgery.
- Failed ET for AIOD does not negatively impact outcomes for subsequent open surgery.
- Open surgery after failed ET ensures limb salvage.
Objectives:
To compare patient outcomes of primary open operation for aortoiliac occlusive disease (AIOD) with those of secondary open operations for failed endovascular therapy (ET) of AIOD.
Design:
A retrospective cohort study was performed analyzing demographic characteristics, comorbidities, and outcomes.
Setting:
Affiliated Veterans Affairs Hospital from January 1, 1998, through March 31, 2010.
Patients:
Patients who underwent primary open operation for AIOD or secondary open operation for failed ET of AIOD.
Main Outcome Measures:
Overall survival and limb salvage.
Results:
Primary open operations (n = 153) were 67 aortobifemoral grafts (43.8%), 38 axillobifemoral grafts (24.8%), and 48 femoral-femoral grafts (31.4%). Secondary open operations (n = 35) were 28 aortobifemoral grafts (80.0%), 5 axillobifemoral grafts (14.3%), and 2 femoral-femoral grafts (5.7%). Mean (SD) 5-year survival was 48.2% (5.6%) and 66.8% (10.0%), respectively, for patients undergoing primary vs secondary open surgery for AIOD (P = .01). There were 7 amputations during a mean follow-up of 3 years, all in the primary open surgery group.
Conclusions:
Despite a higher proportion of coronary artery disease and a 20% conversion of claudication to critical limb ischemia after failed ET for AIOD, survival was longer in patients undergoing secondary vs primary open surgery. Patients who underwent open surgery after failed ET for AIOD did not require amputation. Failed ET for AIOD does not lead to worse outcomes for patients undergoing open surgery for AIOD.
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