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Updated: May 18, 2026

Imaging Features of Systemic Sclerosis-Associated Interstitial Lung Disease
Published on: June 16, 2020
[Special features of systemic sclerosis in men]
Besma Ben Dhaou1, Fatma Derbali, Zohra Aydi
1Service de medecine interne. Hopital Habib Thameur, Tunis, Tunisie.
Background:
Systemic sclerosis (SS) is a generalized disorder of connective tissue and microvasculature characterized by tissue fibrosis and obliteration of the vessels. Several features of systemic scleroderma in men are discussed in the literature.
Aim:
To investigate the initial clinical features, evolution and prognosis of systemic sclerosis in men.
Methods:
Patients with systemic sclerosis based on ACR's criteria were included. In this retrospective study we compared a cohort of men to a cohort of women, diagnosed between 2000 and 2010 in department of internal medicine.
Results:
Fifty four patients were included amongst which nine men. The mean follow-up duration was 39.5 months. A higher proportion of cardiac, renal and lung involvement were noted at diagnosis Localized cutaneous sclerosis was predominant in men.
Conclusion:
This work has highlighted several features of systemic sclerosis encountered in men. These results warrant confirmation by analyzing a larger population.
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