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Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

Combination Therapies and Personalized Medicine

Combination Therapies and Personalized Medicine

Combining two or more treatment methods increases the life span of cancer patients while reducing damage to vital organs or tissue from the overuse of a single treatment. Combination therapy also targets different cancer-inducing pathways, thus reducing the chances of developing resistance to treatment.
The combination of the drug acetazolamide and sulforaphane is a good example of combination therapy to treat cancer. The cells in the interior of a large tumor often die due to the hypoxic and...

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

Targeted Cancer Therapies

Targeted Cancer Therapies

The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against specific...

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Related Experiment Video

Updated: May 18, 2026

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

Published on: August 4, 2020

Personalized surgical therapy.

J-C Tonn¹, N Thon, O Schnell

¹Department of Neurosurgery, Ludwig-Maximilians-University, Munich, Germany. joerg.christian.tonn@med.uni-muenchen.de

Annals of Oncology : Official Journal of the European Society for Medical Oncology

|September 19, 2012

Summary

This summary is machine-generated.

Personalized surgical therapy, including microsurgery and stereotactic biopsy, is key for managing gliomas. This approach aims to improve outcomes by considering individual patient factors and tumor characteristics for better glioma treatment.

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Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality

Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality

Published on: April 5, 2024

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Last Updated: May 18, 2026

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

3D Planning and Printing of Patient Specific Implants for Reconstruction of Bony Defects

Published on: August 4, 2020

Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality

Pioneering Patient-Specific Approaches for Precision Surgery Using Imaging and Virtual Reality

Published on: April 5, 2024

Area of Science:

Neuro-oncology
Surgical Oncology
Neurosurgery

Background:

Gliomas are diffuse brain tumors infiltrating functional tissue, making curative surgery challenging.
Despite infiltrative nature, tumor resection remains a cornerstone of glioma management.
Surgical goals include histological/molecular evaluation, decompression, and cytoreduction.

Framework:

Integrating personalized surgical therapy into glioma prognostic networks.
Considering both low- and high-grade gliomas.
Focus on tailoring treatment to individual patient and tumor characteristics.

Implementation:

Microsurgery for debulking and cytoreduction.
Stereotactic biopsy for accurate diagnosis and molecular profiling.
Practical considerations for applying personalized approaches.

Implications:

Enhanced prognostic accuracy for gliomas.
Optimized surgical strategies for improved patient outcomes.
Advancing the field of precision medicine in neuro-oncology.