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Related Experiment Video

Updated: May 18, 2026

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Quantifying Infra-slow Dynamics of Spectral Power and Heart Rate in Sleeping Mice

Published on: August 2, 2017

A sound sleep.

Rudra Prosad Goswami¹, Swati Mondal, Subrata Basu

¹Department of Medicine, Institute of Post Graduate Medical Education and Research, Kolkata, India.

Indian Journal of Critical Care Medicine : Peer-Reviewed, Official Publication of Indian Society of Critical Care Medicine

|September 19, 2012

Summary

Acute benzodiazepine poisoning can be challenging to diagnose without a clear history. This case highlights unique MRI findings of globus pallidus T2 hyperintensity as a key diagnostic indicator.

Keywords:

Benzodiazepine India MRI bilateral basal ganglia hyperintensity poisoning

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Area of Science:

Neurology
Toxicology
Radiology

Background:

Benzodiazepine poisoning is common but diagnosis can be difficult without a history.
Clinical assessment, urine assays, and imaging are crucial for diagnosis.

Observation:

A case of acute benzodiazepine poisoning presented without a history of drug intake.
Key clinical signs included unarousable state and obstructive apnea.
Brain MRI revealed symmetrical isolated globus pallidus T2 hyperintensity.

Findings:

The MRI finding of isolated bilateral basal ganglia T2-weighted hyperintensity is reported.
This specific imaging finding is associated with acute benzodiazepine poisoning.

Implications:

This case expands the understanding of neuroimaging findings in benzodiazepine poisoning.
Highlights the importance of MRI in diagnosing poisoning when history is absent.
Suggests T2 hyperintensity in the globus pallidus as a potential diagnostic marker.