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Published on: January 2, 2013
Expanding role of a blood center
Jaisy Mathai1, Sulochana P Vasu, Sathyabhama Subhadramma
1Department of Transfusion Medicine, Sree Chitra Tirunal Institute for Medical Sciences and Technology, Thiruvananthapuram, Kerala, India.
Insights
Approximately 1% of healthy blood donors have undetected hypertension. This study highlights the importance of screening for hypertension in seemingly healthy individuals, with higher BMI noted in hypertensive donors.
Area of Science:
- Cardiology
- Public Health
- Transfusion Medicine
Background:
- Undetected hypertension poses a significant public health risk.
- Blood donors represent a segment of the healthy population, offering an opportunity for screening.
Purpose of the Study:
- To estimate the proportion of undetected hypertension among prospective blood donors.
- To compare demographic and anthropometric data between hypertensive and normotensive blood donors.
Main Methods:
- Prospective study involving blood donors deferred due to hypertension.
- Comparison with age- and sex-matched normotensive control donors.
- Hypertension assessment based on WHO-ISH and US JNC criteria.
Main Results:
- Approximately 0.95% of healthy blood donors presented with undetected hypertension.
- The mean age of hypertensive donors at detection was 35.44 ± 7.69 years.
- Hypertensive donors exhibited a significantly higher Body Mass Index (BMI) compared to controls (P < 0.0001).
Conclusions:
- Around 1% of healthy individuals screened through blood donation may have undiagnosed hypertension.
- This finding provides a preliminary estimate of undetected hypertension in the local healthy population.
- Elevated BMI is associated with hypertension in this donor cohort.
Materials And Methods:
The study was performed on prospective donors who reported to the Department of Transfusion Medicine. Individuals deferred due to hypertension contributed the study population. They were compared with age and sex matched donor controls. Demographic details were recorded in a proforma. On identification of a hypertensive individual, consequent two comparable donors were taken as controls with a total of 50 hypertensive subjects. Hypertensive status of the subjects were assessed based on the criteria formulated by the WHO-ISH and US Seventh Joint National Committee report on prevention, detection, evaluation and treatment of high blood pressure.
Results:
About 0.95% of healthy blood donors had undetected hypertension. Mean age at detection of hypertension in the study group was 35.44 ± 7.69 years. Higher BMI was observed in the hypertensive group compared to normotensive control group with P value significant at 0.0001.
Conclusion:
About 1% of healthy individuals were found to have undetected hypertension. Though the study was not designed to determine the prevalence of hypertension in the region, it is a rough estimate of the proportion of undetected hypertension in the local population as donors are considered as representative of healthy population.
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