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Celiac artery compression syndrome: an experience in a single institution in taiwan
Jen-Wei Chou1, Chih-Ming Lin, Chun-Lung Feng
1School of Medicine, China Medical University, Taichung 40402, Taiwan ; Division of Gastroenterology and Hepatology, Department of Internal Medicine, China Medical University Hospital, 2 Yude Road, North District, Taichung 40447, Taiwan.
Insights
Celiac artery compression syndrome (CACS), a rare vascular condition, presents with postprandial pain, vomiting, and weight loss. This study investigates CACS features, its association with superior mesenteric artery syndrome (SMAS), and treatment outcomes in Taiwan.
Area of Science:
- Vascular Surgery
- Gastroenterology
- Rare Diseases
Background:
- Celiac artery compression syndrome (CACS), also known as median arcuate ligament (MAL) syndrome, is a rare vascular disorder.
- Clinical features include postprandial pain, vomiting, and weight loss, stemming from celiac artery compression.
- CACS is infrequently reported in Asian populations, with limited treatment guidelines available.
Purpose of the Study:
- To examine the clinical characteristics of CACS patients.
- To explore the association between CACS and superior mesenteric artery syndrome (SMAS).
- To analyze treatment strategies and patient outcomes for CACS within a single Taiwanese institution.
Main Methods:
- Retrospective analysis of CACS patient data.
- Evaluation of clinical presentations, diagnostic findings, and treatment interventions.
- Assessment of patient outcomes and prognosis post-treatment.
Main Results:
- Detailed analysis of CACS clinical manifestations and etiological factors.
- Investigation into the co-occurrence and impact of SMAS in CACS patients.
- Presentation of treatment modalities and their effectiveness in the studied cohort.
Conclusions:
- CACS presents unique challenges in diagnosis and management due to its rarity.
- Understanding the association with SMAS is crucial for comprehensive patient care.
- This study provides valuable insights into CACS in a Taiwanese population, aiding future therapeutic strategies.
Abstract:
Celiac artery compression syndrome (CACS) or median arcuate ligament (MAL) syndrome is a rare vascular disease. The clinical manifestations of CACS include the triad of postprandial pain, vomiting, and weight loss. The pathogenesis of CACS is the external compression of celiac artery by the MAL or celiac ganglion. Moreover, some authors also reported the compression with different etiologies, such as neoplasms of pancreatic head, adjacent duodenal carcinoma, vascular aneurysms, aortic dissection, or sarcoidosis. In the literature, most cases of CACS were reported from Western countries. In contrast, this disease was seldom reported in Oriental countries or regions, including Taiwan. Superior mesenteric artery syndrome (SMAS) is also a rare disease characterized by compression of the third portion of the duodenum by the SMA. The clinical features of SMAS are postprandial pain, vomiting, and weight loss. To date, there are no guidelines to ensure the proper treatment of patients with CACS because of its low incidence. Thus, tailored therapy for patients with CACS remains a challenge as well as the prediction of clinical response and prognosis. The aim of our present study was to investigate the clinical features, the association with SMAS, treatments, and outcomes of patients with CACS in a single institution in Taiwan.
