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Reversible blindness in bilateral optic neruritis associated with nasal flu vaccine
Binocular Vision & Strabology Quarterly, Simms-Romano'S
|September 20, 2012
Summary
This case report suggests a link between the nasal flu vaccine and optic neuritis in a child. Further research is needed to confirm this association between vaccination and vision loss.
Area of Science:
- Ophthalmology
- Neurology
- Vaccinology
Background:
- Optic neuritis has been anecdotally linked to various vaccines, including influenza, hepatitis B, and anthrax.
- The Live Attenuated Influenza Vaccine (LAIV) is administered nasally.
Observation:
- A 13-year-old male presented with bilateral optic neuritis following nasal flu vaccination.
- Clinical evaluation included neuro-ophthalmologic examination, MRI, visual field testing, and laboratory analyses.
Findings:
- MRI revealed inflammation and enlargement of the optic chiasm and distal optic nerves.
- No infectious, vascular, granulomatous, viral, or immune-related causes were identified.
- The patient showed partial vision improvement with methylprednisolone treatment.
Implications:
- This case presents compelling evidence suggesting LAIV as a potential cause of optic neuritis.
- Highlights the importance of considering vaccination history in cases of unexplained optic neuritis.
- Underscores the need for vigilance regarding potential adverse events following immunization.
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