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Postinflammatory elastolysis and cutis laxa. A case report.

P G Lewis1, A F Hood, N K Barnett

  • 1Department of Dermatology, Johns Hopkins University School of Medicine, Baltimore, Maryland.

Journal of the American Academy of Dermatology
|January 1, 1990
PubMed
Summary
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Postinflammatory elastolysis and cutis laxa, a rare condition causing skin atrophy, is now reported in a North American child. This case expands the known geographic and demographic distribution of this rare elastolytic disorder.

Area of Science:

  • Dermatology
  • Genetics
  • Pathology

Background:

  • Postinflammatory elastolysis and cutis laxa is an extremely rare genetic connective tissue disorder.
  • Previously, this condition was documented exclusively in pediatric patients from Africa and South America.
  • The disease manifests with an initial rash followed by rapid elastic tissue degradation, leading to significant skin laxity and disfigurement.