Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma Virus (RSV) and Cancer

Rous Sarcoma virus or RSV was discovered by F. Peyton Rous in the year 1911 as a filterable transmissible agent that could cause tumors in chickens. He won a Nobel Prize for this discovery in 1966. His experiments clearly demonstrated that some cancers could be caused by infectious agents and led to the discovery of many more cancer-causing viruses in animals as well as humans.
RSV is a retrovirus that contains two copies of a plus-strand RNA genome. Its genome consists of four main open...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Early-stage mantle cell lymphoma: a retrospective analysis from the International Lymphoma Radiation Oncology Group (ILROG).

Annals of oncology : official journal of the European Society for Medical Oncology·2017

Same author

The Intergroup Rhabdomyosarcoma Study Group (IRSG): Major Lessons From the IRS-I Through IRS-IV Studies as Background for the Current IRS-V Treatment Protocols.

Sarcoma·2008

Same author

Intensity-modulated radiation therapy.

Journal of surgical oncology·2008

Same author

Second surgery for recurrent pilocytic astrocytoma in children.

Pediatric neurosurgery·2001

Same author

Improved outcome for patients with middle ear rhabdomyosarcoma: a children's oncology group study.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology·2001

Same author

Prognostic implications for gadolinium enhancement of the meninges in low-grade astrocytomas of childhood.

Pediatric neurosurgery·2001

Search research articles

Related Experiment Video

Updated: May 18, 2026

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

Radiotherapy for rhabdomyosarcoma: indications and outcome.

S A Terezakis¹, M D Wharam

¹Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.

Clinical Oncology (Royal College of Radiologists (Great Britain))

|September 20, 2012

Summary

Rhabdomyosarcoma treatment has advanced through refined therapies and improved imaging for precise radiation. Advanced techniques like intensity-modulated radiotherapy and proton therapy offer better outcomes while minimizing toxicity.

More Related Videos

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Published on: September 13, 2019

Related Experiment Videos

Last Updated: May 18, 2026

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Magnetic Resonance-Guided High Intensity Focused Ultrasound Generated Hyperthermia: A Feasible Treatment Method in a Murine Rhabdomyosarcoma Model

Published on: January 13, 2023

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Tumorsphere Derivation and Treatment from Primary Tumor Cells Isolated from Mouse Rhabdomyosarcomas

Published on: September 13, 2019

Area of Science:

Pediatric oncology
Radiation oncology
Medical imaging

Background:

Rhabdomyosarcoma is the most common childhood soft tissue sarcoma.
Clinical outcomes have improved due to intensified and refined treatment strategies.
Diagnostic imaging advances enhance staging and radiation field design.

Purpose of the Study:

To review the role of radiation therapy in rhabdomyosarcoma treatment.
To discuss site-specific considerations and advanced radiotherapy techniques.
To highlight ongoing research for reducing radiation toxicity.

Main Methods:

Review of Intergroup Rhabdomyosarcoma Study Group findings.
Analysis of advancements in diagnostic imaging.
Evaluation of conformal radiotherapy, intensity-modulated radiotherapy, and proton therapy.

Main Results:

Radiation therapy is integral to rhabdomyosarcoma management.
Advanced techniques are beneficial for sites near critical structures.
Site-specific factors influence local therapy choices and prognosis.

Conclusions:

Refined radiotherapy techniques improve rhabdomyosarcoma treatment efficacy.
Minimizing radiation dose and volume is crucial for reducing late toxicity.
Ongoing research aims to enhance the therapeutic ratio in rhabdomyosarcoma care.