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Updated: May 18, 2026

Inspiratory Muscle Training as an Adjunct to the Treatment of Weaning Failure in Critically Ill Patients: A Practical Guide
Published on: January 30, 2026
Failed weaning from mechanical ventilation and cardiac dysfunction
Jahan Porhomayon1, Peter Papadakos, Nader D Nader
1VA Western New York Healthcare System, Division of Critical Care Medicine, Department of Anesthesiology and Medicine, Buffalo School of Medicine and Biomedical Sciences, The State University of New York, Buffalo, NY 14215, USA.
Abstract:
Failure to transition patient from controlled mechanical ventilation to spontaneous breathing trials (SBTs) in a timely fashion is associated with significant morbidity and mortality in the intensive care unit. In addition, weaning failures are common in patients with limited cardiac reserves. Recent advances in cardiac echocardiography and laboratory measurement of serum biomarkers to assess hemodynamic response to SBT may provide additional information to guide clinicians to predict weaning outcome.
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