Pancortins interact with amyloid precursor protein and modulate cortical cell migration

Heather C Rice1, Matthew Townsend, Jilin Bai

  • 1Center for Neurologic Diseases, Brigham and Women's Hospital, and Harvard Medical School, Boston, MA 02115, USA.

Development (Cambridge, England)
|September 21, 2012
PubMed
Summary

Amyloid precursor protein (APP) interacts with pancortins, influencing neuronal precursor cell migration during brain development. Different pancortin isoforms have opposing roles, highlighting their combined function with APP in cortical development.

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