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Pancytopenia in systemic lupus erythematosus related to azathioprine
1Department of Rheumatology, Dr. Daniel den Hoed Clinic, Rotterdam, The Netherlands.
Journal of Internal Medicine
|January 1, 1990
Abstract:
A patient with systemic lupus erythematosus (SLE) developed pancytopenia when azathioprine (first 2.0 mg kg-1 day-1, then 2.5 mg kg-1 day-1) was added to prednisone for active SLE. This unusual toxic effect of azathioprine occurred during the reduction of corticosteroid dosage. After discontinuation of azathioprine, clinical and haematological recovery occurred.
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