Comparison between Humphrey Field Analyzer and Micro Perimeter 1 in normal and glaucoma subjects

Area of Science:

• Ophthalmology
• Visual Psychophysics
• Medical Devices

Background:

• Glaucoma diagnosis and monitoring rely on visual field testing.
• Automated static threshold perimetry is a standard method.
• Micro Perimeter 1 (MP1) offers an alternative fundus perimetry approach.

Purpose of the Study:

• To correlate visual field test results from MP1 and Humphrey Field Analyzer (HFA).
• To compare the sensitivity of MP1 and HFA in healthy and glaucoma subjects.
• To identify potential differences in differential light sensitivity measurements.

Main Methods:

• 45 eyes with glaucoma and 21 healthy eyes were studied.
• Differential light sensitivity was measured at 21 corresponding points using MP1 and HFA.
• Standardized Goldmann III stimulus and presentation time were employed.

Main Results:

• MP1 and HFA showed significant differences in mean light thresholds for both groups.
• A significant positive correlation was found between MP1 and HFA results in both controls (r=0.439) and glaucoma subjects (r=0.812).
• MP1 demonstrated higher sensitivity in detecting glaucomatous vision loss.

Conclusions:

• Significant and reproducible differences exist between MP1 and HFA differential light thresholds.
• A correction factor of 17.271 was identified for comparing MP1 and HFA.
• MP1 shows promise for enhanced sensitivity in glaucoma progression monitoring.