Related Experiment Video

Updated: May 18, 2026

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis
18:11

A Research Method For Detecting Transient Myocardial Ischemia In Patients With Suspected Acute Coronary Syndrome Using Continuous ST-segment Analysis

Published on: December 28, 2012

Effects of percutaneous coronary intervention on depressive symptoms in chronic stable angina patients

Mahn-Won Park1, Ji-Hun Kim, Sung-Ho Her

  • 1Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Republic of Korea.

Psychiatry Investigation
|September 21, 2012
PubMed

Insights

Percutaneous coronary intervention (PCI) may increase the risk of depression in patients with coronary artery disease (CAD). Routine assessment for PCI-related depressive symptoms in chronic stable angina (CSA) patients is recommended.

Area of Science:

  • Cardiology
  • Psychiatry
  • Clinical Medicine

Background:

  • Depression affects 20% of outpatients with coronary artery disease (CAD).
  • Depression is a known risk factor for adverse cardiac events and mortality in CAD patients.
  • The impact of percutaneous coronary intervention (PCI) on depressive symptoms in chronic stable angina (CSA) patients requires investigation.

Purpose of the Study:

  • To evaluate the effect of PCI on depressive symptoms in patients with CSA.
  • To determine if PCI is an independent risk factor for developing depressive symptoms in CSA patients.

Main Methods:

  • A prospective, non-randomized trial included 171 consecutive CSA patients undergoing coronary angiography.
  • Patients were divided into PCI and non-PCI groups.
  • The Beck Depression Inventory II (BDI-II) was administered at baseline and pre-discharge to assess depressive symptoms.

Main Results:

  • The PCI group (37%) was older and had more comorbidities, including joint disease and stroke history, compared to the non-PCI group (63%).
  • Patients undergoing PCI showed a significantly higher mean difference in BDI-II scores from baseline to pre-discharge (OR: 1.266; p<0.001).
  • PCI was independently associated with an increased risk of developing depressive symptoms.

Conclusions:

  • PCI independently contributes to a higher risk of developing depressive symptoms in CSA patients during hospitalization.
  • Routine assessment and management of PCI-related depressive symptoms are warranted.
  • This study highlights the importance of monitoring mental health in CAD patients post-PCI.
Abstract

Keywords:
AngioplastyCoronary artery diseaseDepression

Related Concept Videos

Acute Coronary Syndrome IV: Interprofessional Care01:28

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...
Angina IV: Management01:26

Angina IV: Management

IntroductionThe management of angina requires a comprehensive approach that includes pharmacological therapies, medical procedures, and lifestyle modifications.Pharmacological TherapiesAntiplatelet agents, such as aspirin, clopidogrel, prasugrel, and ticagrelor, play a pivotal role in preventing thrombus formation in patients with angina. These medications inhibit platelet aggregation and reduce the likelihood of myocardial infarction and other cardiovascular events.Anticoagulants, including...
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations01:19

Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations

The pathophysiology of Acute Coronary Syndrome [ACD] involves several key processes:The main underlying cause of ACD is atherosclerosis, a chronic inflammatory disease characterized by the buildup of lipid-laden plaques within the coronary arteries.As the atherosclerotic plaque grows in the coronary artery, it may become unstable due to the formation of a lipid-rich core and a thin fibrous cap. Inflammatory cells within the plaque, such as macrophages, secrete enzymes that degrade the...
Angina III: Clinical Manifestations and Assessment01:29

Angina III: Clinical Manifestations and Assessment

Angina manifests as chest pain, tightness, or squeezing discomfort typically located behind the breastbone. It can radiate to the neck, jaw, shoulders, and inner aspects of the upper arms, most commonly the left arm. Patients may experience shortness of breath, fatigue, profuse sweating, dizziness, indigestion, heartburn, palpitations, anxiety, and vomiting as accompanying symptoms. This pain often lasts a few minutes and is triggered by physical exertion, emotional stress, heavy meals, or cold...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...
Acute Coronary Syndrome III: Diagnostic Studies01:30

Acute Coronary Syndrome III: Diagnostic Studies

Diagnosing acute coronary syndrome or ACS begins with a thorough patient history. Notable symptoms include central, crushing chest pain radiating to the left arm, neck, jaw, or back, along with shortness of breath, sweating (diaphoresis), nausea, vomiting, dizziness, and palpitations.It is crucial to note any history of cardiac illnesses and assess risk factors, including age, gender, smoking, hypertension, diabetes, hyperlipidemia, and a sedentary lifestyle.During physical examination, vital...