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Rhino-orbital fungal infection: two cases report
Yanin Suwan1, Achara Punyawattanaporn, Passorn Preechawai
1Department ofOphthalmology, Faculty of Medicine, Prince ofSongkla University, Hat Yai, Songkhla, Thailand. yaninyona@hotmail.com
Abstract:
Rhino-orbital fungal infections are serious and life threatening complications of immunocompromised host. The authors reported two cases of rapid progressive proptosis and eyelid necrosis of immunocompromised patients who suffered from highly malignant T-celled lymphoblastic leukemia/lymphoma and congenital heart disease with multiple anomalies. Although early diagnosis was made and prompt treatments including medical and surgical interventions were performed, both patients died.
Insights
Rhino-orbital fungal infections are life-threatening in immunocompromised patients. Despite prompt treatment, two patients with leukemia and heart defects succumbed to rapid progression of this severe fungal complication.
Area of Science:
- Ophthalmology
- Infectious Diseases
- Oncology
Background:
- Rhino-orbital fungal infections pose a significant threat to immunocompromised individuals.
- These infections can rapidly progress and lead to severe complications.
Observation:
- Two cases of immunocompromised patients presented with rapidly progressive proptosis and eyelid necrosis.
- Both patients had a history of highly malignant T-cell lymphoblastic leukemia/lymphoma and congenital heart disease with multiple anomalies.
Findings:
- Despite early diagnosis and prompt medical and surgical interventions, both patients experienced a fatal outcome.
- The aggressive nature of the rhino-orbital fungal infection in these complex cases was evident.
Implications:
- Highlights the critical need for heightened vigilance and rapid intervention strategies for rhino-orbital fungal infections in severely immunocompromised patients.
- Underscores the challenges in managing life-threatening fungal infections in patients with complex comorbidities like hematologic malignancies and congenital anomalies.
