[Morphogenesis of complications after long-term intraocular silicon oil filling (clinical histopathological study)]

The question of necessity and time of silicon oil (SO) removal after tamponade for traumatic retinal detachment (TRD) is still controversial. So the study of changes in the eye filled with SO for a long time is of great interest. Histopathologic analysis of 9 enucleated eyes filled with SO for TRD during long-time period (from 6 months till 30 years) was performed. The characteristic change was inflammatory reaction with fibrin membranes surrounding silicon drops and development of proliferative vitreoretinopathy and tractional retinal detachment in the following. In 2 cases the inflammatory process around SO was associated with bone formation. The most severe complication was the imbibition of retina with SO in a vacuole-like manner associated with total atrophy of neural structures. Obtained data show that time for SO removal should be less than 6 months after surgery.