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Prehospital Thrombolysis: A Manual from Berlin
05:52

Prehospital Thrombolysis: A Manual from Berlin

Published on: November 26, 2013

Selection of possible responders to thrombolytic therapy in acute ischemic stroke

Christian Hametner1, Peter Arthur Ringleb, Werner Hacke

  • 1Department of Neurology, University of Heidelberg, Heidelberg, Germany.

Annals of the New York Academy of Sciences
|September 22, 2012
PubMed

Ischemic stroke is one of the leading causes of death and morbidity worldwide, and systemic thrombolytic treatment is still the first-line therapy within 4.5 h from symptom onset. Selecting patients for treatment response is mandatory in any time window but challenging as well. The authors aim to support stroke physicians in their individual decision making. Besides evidence from clinical trials, some suggestions included here exclusively reflect the authors' opinions. This article presents clinical and imaging criteria of selecting patients reasonably, offering causal therapy to a growing number of patients.

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