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A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
Published on: August 12, 2020
Erythema multiforme in a 25-day old neonate
Charlene U Ang-Tiu1, Marie Eleanore O Nicolas
1Section of Dermatology, Department of Medicine, University of the Philippines-Philippine General Hospital, Manila, Philippines.
Pediatric Dermatology
|September 22, 2012
Summary
This case study highlights a rare instance of erythema multiforme in a neonate, presenting with characteristic target lesions. It underscores the importance of recognizing these distinctive skin manifestations even in unusual patient populations.
Area of Science:
- Dermatology
- Neonatology
- Immunology
Background:
- Erythema multiforme is an acute, self-limiting mucocutaneous hypersensitivity reaction.
- Typically presents in young adults, often triggered by infections.
- Rarely diagnosed in the neonatal period.
Observation:
- A 25-day-old infant presented with classic target skin lesions on palms and soles.
- The infant had no other concurrent symptoms or significant medical history.
- Standard laboratory tests and viral titers were unremarkable.
Findings:
- Pathological examination confirmed epidermal changes consistent with erythema multiforme.
- The diagnosis was established despite the patient's young age and lack of typical triggers.
- This case demonstrates an atypical presentation of erythema multiforme.
Implications:
- Emphasizes the need for vigilant diagnosis of erythema multiforme in neonates.
- Highlights that distinctive target lesions are key diagnostic indicators.
- Suggests that atypical presentations warrant thorough dermatopathological evaluation.
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