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Updated: May 18, 2026

In vitro Assessment of Aortic Regurgitation Using Four-Dimensional Flow Magnetic Resonance Imaging
Published on: February 25, 2022
Mechanisms and prediction of aortic regurgitation after TAVI
Anna Sonia Petronio1, Cristina Giannini, Marco De Carlo
1Cardiac Thoracic and Vascular Department, University of Pisa, Pisa, Italy. as.petronio@gmail.com
Abstract:
It has been demonstrated that moderate to severe paravalvular leak (PVL) after transcatheter aortic valve implantation (TAVI) procedures are related to impaired long-term prognosis. Anatomical and procedural factors influence the frequency and severity of PVL. Anatomical predictors of this complication are: annulus dimensions and shape, calcium distribution, angle between the ascending aorta axis and the left ventricular outflow tract (LVOT-AO). Procedural predictors: prosthesis-size-annulus mismatch, valve depth deployment and the acquired experience of the centre. An effort has to be made to optimise valve sizing and deployment.
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