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Related Concept Videos

Heart Valves01:16

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...
Mechanical Ventilation III: Noninvasive Ventilation01:23

Mechanical Ventilation III: Noninvasive Ventilation

Noninvasive positive-pressure ventilation (NIPPV), continuous positive airway pressure (CPAP), and bilevel positive airway pressure (BiPAP) are essential methods in respiratory care. These ventilation techniques offer unique benefits for patients with various respiratory conditions, providing adequate support without requiring intubation. Let's explore how each method is crucial in improving patient outcomes and enhancing respiratory therapy.
Noninvasive Positive-Pressure Ventilation (NIPPV)
Aortic Regurgitation III: Medical Management01:25

Aortic Regurgitation III: Medical Management

Aortic regurgitation (AR) is when the aortic valve does not close or seal properly, leading to backward blood circulation from the aorta into the left ventricle during diastole. Common causes of AR include rheumatic heart disease, congenital valve defects, and aortic root dilation. Managing AR requires a multifaceted approach to alleviate symptoms, preserve left ventricular function, and address the underlying cause of the regurgitation. Patients with symptomatic AR or significant left...
Oxygen Delivering System III: Tracheostomy and T-piece01:23

Oxygen Delivering System III: Tracheostomy and T-piece

Oxygen delivery is critical in clinical care, especially for patients with respiratory disorders or those undergoing surgical procedures. Various systems, such as tracheostomy and the T-piece, deliver oxygen to the lungs, ensuring adequate arterial oxygenation.
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...

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Related Experiment Video

Updated: May 18, 2026

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
11:12

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves

Published on: October 17, 2013

Edwards SAPIEN 3 valve.

Ronald K Binder1, Josep Rodés-Cabau, David A Wood

  • 1St. Paul's Hospital, University of British Columbia, Vancouver, BC, Canada.

Eurointervention : Journal of Europcr in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
|September 22, 2012
PubMed
Summary
This summary is machine-generated.

The new SAPIEN 3 transcatheter heart valve (THV) offers improved features to minimize vascular injury and leakage, ensuring easier and more precise implantation for patients.

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Particle Image Velocimetry Investigation of Hemodynamics via Aortic Phantom
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Last Updated: May 18, 2026

Protocol for Relative Hydrodynamic Assessment of Tri-leaflet Polymer Valves
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Particle Image Velocimetry Investigation of Hemodynamics via Aortic Phantom

Published on: February 25, 2022

Area of Science:

  • Cardiovascular medicine
  • Biomedical engineering
  • Medical devices

Background:

  • The SAPIEN, SAPIEN XT, and earlier transcatheter heart valves (THV) have demonstrated clinical success.
  • Continuous innovation in THV technology is crucial for improving patient outcomes.

Purpose of the Study:

  • To introduce the SAPIEN 3 THV, highlighting its novel features.
  • To detail the design enhancements aimed at improving safety and efficacy.
  • To describe the advancements in the delivery system for better procedural performance.

Main Methods:

  • The SAPIEN 3 THV features a cobalt chromium stent and bovine pericardial leaflets.
  • It incorporates an inner and a new outer polyethylene terephthalate sealing cuff.
  • A new active three-dimensional coaxial positioning catheter is utilized in the delivery system compatible with a 14 Fr expandable sheath.

Main Results:

  • The design aims to reduce the risk of vascular injury.
  • Enhanced features are intended to minimize paravalvular regurgitation.
  • The system facilitates rapid and accurate positioning and implantation.

Conclusions:

  • The SAPIEN 3 THV represents an advancement in balloon-expandable THV technology.
  • Its design incorporates features to enhance safety, reduce complications, and improve procedural efficiency.
  • Further clinical evaluation will confirm the benefits of these new features.