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Prospective, Randomized, and Controlled Study of a Human Umbilical Cord Mesenchymal Stem Cell Injection for Treating Diabetic Foot Ulcers
Published on: March 3, 2023
Partial foot amputation in patients with diabetic foot ulcers
Matthew L Brown1, Wan Tang, Amar Patel
1University of Rochester School of Medicine and Dentistry, Rochester, NY, USA.
Foot & Ankle International
|September 22, 2012
Summary
Partial foot amputations, particularly transmetatarsal and Chopart
Area of Science:
- Podiatric surgery
- Diabetic foot complications
- Amputation outcomes
Background:
- Transtibial amputations (TTA) are common for severe foot ulcers but lead to reduced mobility.
- Partial foot amputations offer a theoretical advantage of an end-bearing limb and improved function.
- Investigating partial foot amputations as an alternative to TTA is crucial for optimizing patient outcomes.
Purpose of the Study:
- To compare the longevity, functional outcomes, and mortality rates of various partial foot amputations against transtibial amputations.
- To determine if partial foot amputations offer a superior alternative to TTA in diabetic patients.
Main Methods:
- Retrospective chart review of diabetic patients undergoing transmetatarsal, Chopart's, calcanectomy, or transtibial amputations.
- Comparison of 5-year mortality, reamputation rates, and validated ambulatory functional outcome scores between amputation types.
Main Results:
- Transmetatarsal amputations showed lower 5-year mortality than TTA (0.30 vs. 0.45) with good ambulatory scores (4.3).
- Chopart's amputations also demonstrated favorable ambulatory scores (4.3) and comparable mortality to TTA.
- Calcanectomy procedures exhibited higher mortality rates and lower ambulatory scores compared to TTA and other partial foot amputations.
Conclusions:
- Transtibial amputation is linked to significant morbidity and mortality.
- Transmetatarsal and Chopart's amputations demonstrate potential for improved survivorship and ambulatory function compared to TTA.
- Further investigation into partial foot amputations is warranted to optimize limb salvage and functional recovery in diabetic patients.
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