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Related Experiment Video

Updated: May 18, 2026

Line Shape Analysis of Dynamic NMR Spectra for Characterizing Coordination Sphere Rearrangements at a Chiral Rhenium Polyhydride Complex

Line Shape Analysis of Dynamic NMR Spectra for Characterizing Coordination Sphere Rearrangements at a Chiral Rhenium Polyhydride Complex

Published on: July 27, 2022

A chirality rewriting cycle mediated by a dynamic cyclen-calcium complex.

Hiroshi Ito¹, Hiroshi Tsukube, Satoshi Shinoda

¹JST, CREST, and Department of Chemistry, Graduate School of Science, Osaka City University, Sugimoto, Sumiyoshi-ku, Osaka 558-8585, Japan.

Chemical Communications (Cambridge, England)

|September 22, 2012

Summary

This study demonstrates a calcium complex that transfers chirality, enabling information to be repeatedly written and erased. This process is key for developing novel chiral materials and dynamic molecular systems.

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Last Updated: May 18, 2026

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Area of Science:

Coordination Chemistry
Supramolecular Chemistry
Chiral Catalysis

Background:

Cyclen-based macrocycles are versatile ligands in coordination chemistry.
Chirality transfer is fundamental for asymmetric synthesis and molecular recognition.
Developing systems for dynamic and reversible control of chirality is an ongoing challenge.

Purpose of the Study:

To investigate the chiral induction capabilities of a novel Ca(2+) complex with a functionalized octadentate cyclen.
To explore the dynamic manipulation of chirality through external chiral inputs.
To establish a molecular system for reversible information storage based on chirality.

Main Methods:

Synthesis and characterization of a calcium(II) complex with an octadentate cyclen ligand bearing pyridine and triazole moieties.
Chirality transfer experiments using an external chiral source.
Dynamic manipulation of chirality via esterification and de-esterification reactions with chiral anions.

Main Results:

The Ca(2+) complex successfully mediated two-point chirality transfer to coordinating pyridine and coumarin groups.
The induced chiral information was demonstrated to be reversibly written, deleted, and rewritten.
Esterification with a chiral anion served as the mechanism for dynamic chirality modulation.

Conclusions:

The developed Ca(2+) complex acts as a platform for efficient and reversible chirality transfer.
This work presents a novel approach for dynamic control and information storage using molecular chirality.
The findings have implications for the design of responsive materials and advanced molecular devices.