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Updated: May 18, 2026

Lineage-reprogramming of Pericyte-derived Cells of the Adult Human Brain into Induced Neurons
Published on: May 12, 2014
Direct lineage conversion: induced neuronal cells and induced neural stem cells
1Institute of Zoology, State Key Laboratory of Reproductive Biology, Chinese Academy of Sciences, Beijing, China.
Abstract:
Cellular reprogramming to neural cells is an area of ongoing study in developmental neuroscience, and recent research has generated remarkable achievements. Several studies have shown that the ectopic expression of specific neural transcription factors can convert terminally differentiated cells into neural cells. Here, we review the most recent progress in the field of induced neuronal (iN) cells and induced neural stem (iNS) cells and their potential clinical applications.
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