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Image artifacts from MR-based attenuation correction in clinical, whole-body PET/MRI

Sune H Keller1, Søren Holm, Adam E Hansen

  • 1Department of Clinical Physiology, Nuclear Medicine and PET, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, 2100 Copenhagen, Denmark. sune@pet.rh.dk

Magma (New York, N.Y.)
|September 22, 2012
PubMed
Abstract

Insights

Integrated PET/MRI systems offer potential advantages over PET/CT, but understanding image artifacts from MR-based attenuation correction (MR-AC) is crucial for accurate clinical interpretation.

Area of Science:

  • Medical Imaging
  • Radiology
  • Nuclear Medicine

Background:

  • Integrated whole-body PET/MRI systems are emerging as alternatives to PET/CT.
  • Successful clinical implementation hinges on understanding novel MR-based attenuation correction (MR-AC) methods.
  • Potential pitfalls and artifacts associated with MR-AC require thorough investigation.

Purpose of the Study:

  • To present and describe common PET/MR image artifacts encountered during routine clinical operations.
  • To highlight the importance of understanding MR-AC-related artifacts for accurate PET/MRI interpretation.
  • To inform the clinical adoption of integrated PET/MRI technology.

Main Methods:

  • Analysis of image artifacts observed in clinical practice using an integrated whole-body PET/MRI system.
  • Focus on artifacts specifically arising from MR-based attenuation correction (MR-AC).
  • Systematic documentation of frequently encountered artifacts during routine operations.

Main Results:

  • Detailed presentation of common PET/MR image artifacts resulting from routine MR-AC.
  • Identification of specific artifact patterns observed in clinical PET/MRI scans.
  • Demonstration of how MR-AC can introduce image quality issues.

Conclusions:

  • Clinical adoption of integrated PET/MRI requires careful interpretation of MR data, MR-AC maps, and PET images.
  • Joint display and interpretation of multimodal data are essential for recognizing MR-AC pitfalls.
  • Ensuring clinically accurate image interpretation necessitates a comprehensive understanding of MR-AC artifacts.

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