Related Experiment Video
Updated: May 18, 2026
08:14
An In Vitro Model for Measuring Immune Responses to Malaria in the Context of HIV Co-infection
Published on: October 6, 2015
[Morbidity and mortality in HIV infection]
M Stöckle1, L Elzi, J K Rockstroh
1Klinik für Infektiologie und Spitalhygiene, Universitätsspital Basel, Petersgraben 4, 4031, Basel, Schweiz.
Der Internist
|September 22, 2012
Summary
Combination antiretroviral therapy (cART) significantly improves HIV prognosis, enabling near-normal life expectancy. However, late diagnosis and co-morbidities present ongoing challenges for long-term HIV management.
Area of Science:
- Immunology
- Virology
- Public Health
Context:
- Combination antiretroviral therapy (cART) has transformed HIV/AIDS outcomes.
- Significant improvements in life expectancy are observed in treated individuals.
- HIV infection can be managed, preventing or restoring immune function.
Purpose:
- To summarize the impact of cART on HIV prognosis.
- To highlight challenges in HIV management.
- To discuss future considerations for aging HIV-infected populations.
Summary:
- cART dramatically improves prognosis for HIV-infected individuals, allowing for near-normal life expectancy.
- Early intervention with cART prevents or reconstitutes immune deficiency.
- Late diagnosis and co-morbidities (viral hepatitis, tumors) contribute to persistent morbidity and mortality, especially in older patients.
Impact:
- cART has shifted HIV from a fatal diagnosis to a manageable chronic condition.
- Understanding remaining challenges is crucial for optimizing long-term HIV care.
- The aging HIV population presents new complexities regarding co-morbidities and healthcare costs.
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