Related Experiment Video

Updated: May 18, 2026

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis
10:26

A Multicenter MRI Protocol for the Evaluation and Quantification of Deep Vein Thrombosis

Published on: June 2, 2015

The incidence of cerebral venous thrombosis: a cross-sectional study

Jonathan M Coutinho1, Susanna M Zuurbier, Majid Aramideh

  • 1Department of neurology, Academic Medical Centre, Meibergdreef 9, 1105 AZ Amsterdam, The Netherlands. j.coutinho@amc.uva.nl

Stroke
|September 22, 2012
PubMed

Insights

The incidence of adult cerebral venous thrombosis (CVT) is higher than previously thought, with an overall rate of 1.32 per 100,000 person-years. Higher CVT rates were observed in women aged 31-50.

Area of Science:

  • Neurology
  • Epidemiology
  • Public Health

Background:

  • Cerebral venous thrombosis (CVT) is a rare but serious condition.
  • Accurate incidence data is crucial for understanding disease burden and resource allocation.

Purpose of the Study:

  • To determine the incidence of adult cerebral venous thrombosis (CVT) in two Dutch provinces.
  • To provide updated epidemiological data on CVT.

Main Methods:

  • Retrospective cross-sectional study in 19 hospitals across two Dutch provinces (2008-2010).
  • Case identification using hospital financial coding and ICD-9 codes, with manual medical record review.
  • Population data obtained from the Dutch National Bureau of Statistics.

Main Results:

  • Identified 94 confirmed cases of cerebral venous thrombosis (CVT) from 9,270 potential cases.
  • Overall CVT incidence was 1.32 per 100,000 person-years (95% CI, 1.06-1.61).
  • Incidence in women aged 31-50 years was significantly higher at 2.78 per 100,000 person-years (95% CI, 1.98-3.82).

Conclusions:

  • The incidence of adult cerebral venous thrombosis (CVT) is likely underestimated by previous studies.
  • Findings highlight a potentially higher public health burden of CVT than currently recognized.
Abstract

Related Concept Videos

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies01:20

Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies

The key difference between Superficial Vein Thrombosis (SVT) and Deep Vein Thrombosis (DVT) lies in their location and severity.Clinical ManifestationsSVT typically presents with localized pain, tenderness, and redness along the course of a superficial vein, often accompanied by a palpable, cord-like structure under the skin. This condition is usually less dangerous than DVT but can be uncomfortable and may lead to complications such as cellulitis or, rarely, a clot extension into the deep...
Venous Thrombosis I: Introduction01:30

Venous Thrombosis I: Introduction

Venous thrombosis, the most common disorder of the veins, involves the formation of a thrombus or blood clot associated with vein inflammation. It can be classified as either superficial vein thrombosis or deep vein thrombosis.Superficial Vein Thrombosis: This involves the formation of a thrombus in a superficial vein, usually the greater or lesser saphenous vein. Though less severe than deep vein thrombosis (DVT), SVT can lead to complications if untreated.Deep Vein Thrombosis (DVT): This...
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Hemorrhagic Stroke l: Introduction01:17

Hemorrhagic Stroke l: Introduction

A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
Hemorrhagic Stroke ll: Pathophysiology01:29

Hemorrhagic Stroke ll: Pathophysiology

A hemorrhagic stroke develops when a cerebral blood vessel ruptures, allowing blood to escape into the surrounding brain tissue, as in intracerebral hemorrhage (ICH), or into the subarachnoid space, as in subarachnoid hemorrhage (SAH). Because the skull is a rigid compartment, the sudden presence of extravascular blood rapidly increases intracranial pressure and compresses adjacent neural structures, leading to immediate tissue injury and impaired cerebral perfusion.Mass Effect and Primary...
Aneurysm II: Clinical Manifestations and Diagnostic Studies01:21

Aneurysm II: Clinical Manifestations and Diagnostic Studies

Thoracic, aortic arch and abdominal aneurysms are significant vascular conditions that can present with various clinical manifestations and lead to serious complications. Understanding these manifestations and the appropriate diagnostic studies is essential for effective management and treatment.Thoracic Aortic AneurysmsThoracic aortic aneurysms often remain asymptomatic until they reach a size that impinges on adjacent structures. They typically cause deep, diffuse chest pain that radiates to...