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Published on: March 27, 2018
Risk factors for low cardiac output syndrome after coronary artery bypass grafting surgery
Michel Pompeu Barros de Oliveira Sá1, Joana Rosa Costa Nogueira, Paulo Ernando Ferraz
1michel_pompeu@yahoo.com.br
Insights
This study identified key risk factors for low cardiac output syndrome (LCOS) after coronary artery bypass grafting (CABG). Older age, on-pump surgery, emergency procedures, incomplete revascularization, and reduced ejection fraction increase LCOS risk.
Area of Science:
- Cardiovascular Surgery
- Critical Care Medicine
- Clinical Risk Factor Analysis
Background:
- Low cardiac output syndrome (LCOS) is a significant complication following cardiac surgery, associated with high morbidity and mortality.
- Identifying risk factors for LCOS is crucial for improving patient outcomes after coronary artery bypass grafting (CABG).
Purpose of the Study:
- To identify independent risk factors for LCOS in patients undergoing CABG.
- To provide data for risk stratification and prevention strategies in cardiovascular surgery.
Main Methods:
- A historical prospective study involving 605 consecutive patients undergoing CABG.
- Evaluation of 12 preoperative and 7 intraoperative variables.
- Univariate and multivariate logistic regression analysis to determine independent risk factors.
Main Results:
- The incidence of LCOS was 14.7%, with a 52.8% mortality rate among affected patients.
- Independent risk factors identified: age > 60 years (OR 2.00), on-pump CABG (OR 2.16), emergency surgery (OR 4.71), incomplete revascularization (OR 2.62), and ejection fraction <50% (OR 2.62).
Conclusions:
- Age over 60, on-pump CABG, emergency surgery, incomplete revascularization, and ejection fraction below 50% are significant independent risk factors for LCOS.
- These findings can inform clinical practice to mitigate LCOS risk in CABG patients.
Objectives:
Low cardiac output syndrome (LCOS) is a serious complication after cardiac surgery and is associated with significant morbidity and mortality. The aim of this study is to identify risk factors for LCOS in patients undergoing coronary artery bypass grafting (CABG) in the Division of Cardiovascular Surgery of Pronto Socorro Cardiológico de Pernambuco - PROCAPE (Recife, PE, Brazil).
Methods:
A historical prospective study comprising 605 consecutive patients operated between May 2007 and December 2010. We evaluated 12 preoperative and 7 intraoperative variables. We applied univariate and multivariate logistic regression analysis.
Results:
The incidence of LCOS was 14.7% (n = 89), with a lethality rate of 52.8% (n = 47). In multivariate analysis by logistic regression, four variables remained as independent risk factors: age > 60 years (OR 2.00, 95% CI 1.20 to 6.14, P = 0.009), on-pump CABG (OR 2.16, 95% CI 1.40 to 7.08, P = 0.006), emergency surgery (OR 4.71, 95% CI 1.34 to 26.55, P = 0.028), incomplete revascularization (OR 2.62, 95% CI 1.32 to 5.86, P = 0.003), and ejection fraction <50%.
Conclusions:
This study identified the following independent risk factors for LCOS after CABG: age> 60 years of off-pump CABG, emergency surgery, incomplete CABG and ejection fraction <50%.
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