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Cell-surface Signaling

Cell-surface Signaling

Hormones—or any molecule that binds to a receptor, known as a ligand—that are lipid-insoluble (water-soluble) are not able to diffuse across the cell membrane. In order to be able to affect a cell without entering it, these hormones bind to receptors on the cell membrane. When a first messenger, a hormone, binds to a receptor, a signal cascade is set off, causing second messengers, proteins inside the cell, to become activated, resulting in downstream effects.

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Related Experiment Video

Updated: May 18, 2026

Identifying Cell Surface Markers of Primary Neural Stem and Progenitor Cells by Metabolic Labeling of Sialoglycan

Identifying Cell Surface Markers of Primary Neural Stem and Progenitor Cells by Metabolic Labeling of Sialoglycan

Published on: September 7, 2019

Beyond surface markers with a universal cell secretion assay

Lydie Trautmann¹

¹Division of Infectious Diseases, Vaccine and Gene Therapy Institute Florida VGTIFL, Port Saint Lucie, Florida 34987, USA. ltrautmann@vgtifl.org

Cytometry. Part a : the Journal of the International Society for Analytical Cytology

|September 22, 2012

Summary

No abstract available in PubMed .

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