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Related Experiment Videos

Granulomatous prostatitis induced by capsule-deficient cryptococcal infection.

S Milchgrub1, E Visconti, J Avellini

  • 1Department of Pathology, Lutheran Medical Center, Brooklyn, New York.

The Journal of Urology
|February 1, 1990
PubMed
Summary

A case of granulomatous prostatitis caused by Cryptococcus was successfully treated with transurethral prostatectomy and ketoconazole. The patient recovered fully, showing no signs of infection after 22 months.

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Area of Science:

  • Urology
  • Mycology
  • Pathology

Background:

  • Prostatism is a common condition in older men.
  • Granulomatous prostatitis can have various causes, necessitating accurate diagnosis.

Observation:

  • A 59-year-old man presented with prostatism and was treated with transurethral prostatectomy and ketoconazole.
  • Microscopic examination revealed acute and chronic prostatitis with granulomatous lesions.

Findings:

  • Capsular-deficient Cryptococcal organisms were identified within the granulomatous lesions.
  • The patient showed a complete recovery with no evidence of systemic or local infection at 22 months post-treatment.

Implications:

  • This case highlights Cryptococcus as a potential cause of granulomatous prostatitis.

Related Experiment Videos

  • Successful management involves antifungal therapy and potentially surgical intervention.
  • Differential diagnosis of granulomatous prostatitis should include fungal infections.