Related Experiment Video

Updated: May 18, 2026

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
12:45

Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

Published on: December 11, 2017

[Cardiac complications and heart rhythm variability in the late post-stroke period]

A V Foniakin, L A Geraskina, V A Shandalin

    Klinicheskaia Meditsina
    |September 25, 2012
    PubMed

    Insights

    Patients who experienced cardiac complications after ischemic stroke showed reduced heart rhythm variability (HRV). Lower HRV may indicate a higher risk of adverse cardiac events following a stroke.

    Area of Science:

    • Cardiology
    • Neurology
    • Medical Statistics

    Background:

    • Ischemic stroke survivors are at increased risk for cardiac complications.
    • Heart rhythm variability (HRV) is a marker of autonomic nervous system function.
    • The relationship between HRV and post-stroke cardiac events requires further investigation.

    Purpose of the Study:

    • To investigate the association between heart rhythm variability (HRV) and the incidence of cardiac complications in patients following an ischemic stroke.
    • To identify potential predictors of cardiac events in the post-stroke period.

    Main Methods:

    • Prospective study involving 90 patients with ischemic stroke and sinus rhythm.
    • 24-hour Holter monitoring was performed 21 days post-stroke for HRV analysis (temporal and spectral).
    • Patients were followed for a median of 23 months to track cardiac events.

    Main Results:

    • 11% of patients developed major cardiac complications (myocardial infarction, unstable angina, cardiac failure, or sudden death).
    • Patients who experienced cardiac complications were older and had a history of coronary heart disease (CHD).
    • Significantly lower spectral characteristics of HRV were observed in patients who developed cardiac complications (p < 0.05).

    Conclusions:

    • Reduced heart rhythm variability is associated with an increased risk of cardiac complications after ischemic stroke.
    • HRV analysis may serve as a valuable tool for risk stratification in post-stroke patients.
    • Early identification of patients with low HRV could facilitate timely cardiac interventions.

    Related Concept Videos

    Dysrhythmias V: Evaluating Dysrhythmias01:30

    Dysrhythmias V: Evaluating Dysrhythmias

    Dysrhythmias, also known as arrhythmias, are disturbances in the heart's rhythm that range from benign to life-threatening. A thorough evaluation is crucial for appropriate management and involves a comprehensive medical history, physical examination, and various diagnostic tests.Medical HistorySymptoms: Collect detailed information on palpitations, dizziness, syncope, chest pain, and fatigue. Note their onset, frequency, and triggers.Previous Cardiac Issues: Document any history of heart...
    Pulse rhythm01:30

    Pulse rhythm

    Pulse rhythm refers to the pattern of pulsations within specific intervals, offering valuable insights into the regularity or irregularity of the heart's beats as observed through the pattern of pulsation within specific intervals. A regular pulse exhibits a consistent heart rate with uniform waveforms and pulsation force, variations of which can be classified as normal, weak, or bounding.
    Conversely, an irregular pulse pattern is termed dysrhythmia, stemming from disruptions in cardiac muscle...
    Mechanism of Cardiac Arrhythmias01:28

    Mechanism of Cardiac Arrhythmias

    Arrhythmias are irregular heart rhythms occurring when the heart's electrical impulses become abnormal. These disturbances can lead to various symptoms, depending on their severity and the underlying cause. Some common factors contributing to arrhythmias include hypoxia, ischemia, electrolyte imbalances, excessive catecholamine exposure, drug toxicity, and muscle overstretching. Arrhythmias can be classified into two main types based on the rate and site of origin of abnormal heart rhythms.
    Disturbances in Heart Rhythm01:29

    Disturbances in Heart Rhythm

    Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
    Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
    Dysrhythmias III: Characteristics of Dysrhythmias01:29

    Dysrhythmias III: Characteristics of Dysrhythmias

    Dysrhythmias, also known as arrhythmias, are irregular heart rhythms that result from abnormal electrical activity in the heart, affecting its ability to circulate blood efficiently. Tachyarrhythmias, a subset of dysrhythmias, are characterized by abnormally fast heart rates exceeding 100 beats per minute. Here are some types of tachyarrhythmias with their distinct ECG features:Sinus Tachycardia:Sinus tachycardia presents a regular heart rhythm with an increased rate of 101-180 beats per minute.
    Heart Failure III: Clinical Manifestations01:26

    Heart Failure III: Clinical Manifestations

    Heart failure (HF) manifests primarily as dyspnea, fatigue, and fluid retention, resulting in peripheral and pulmonary edema. Symptoms may vary depending on which ventricle is more affected, left or right.Left-Sided Heart FailureAlso known as left ventricular failure, this condition results from the left ventricle's inability to fill or eject sufficient blood into the systemic circulation. It leads to pulmonary congestion, which occurs when the left ventricle fails to eject blood effectively...