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In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
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[Visceral leishmaniasis (two case reports)].

J Benes1, M Kabelková, P Holecková

  • 1Klinika infekcních nemocí, 3. LF UK a Nemocnice Na Bulovce, Praha. benes.infekce@seznam.cz

Klinicka Mikrobiologie a Infekcni Lekarstvi
|September 25, 2012
PubMed
Summary
This summary is machine-generated.

Two imported visceral leishmaniasis cases highlight diagnostic challenges in travelers returning from Italy and Croatia. Both patients achieved successful treatment with amphotericin B lipid complex, demonstrating effective therapeutic outcomes.

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Area of Science:

  • Tropical medicine
  • Parasitology
  • Infectious diseases

Context:

  • Reports two cases of imported visceral leishmaniasis in Czech travelers returning from endemic areas in Italy and Croatia.
  • Highlights the potential for leishmaniasis to manifest months to years after travel.
  • Notes the occurrence in an immunocompromised patient undergoing chemotherapy.

Purpose:

  • To describe two cases of imported visceral leishmaniasis.
  • To discuss diagnostic difficulties associated with this parasitic disease.
  • To report successful treatment outcomes.

Summary:

  • Two Czech men contracted visceral leishmaniasis following travel to Italy and Croatia.
  • Diagnosis was challenging, particularly in the patient with a history of chemotherapy for testicular cancer.
  • Both individuals responded well to treatment with amphotericin B lipid complex (Abelcet).

Impact:

  • Underscores the importance of considering imported leishmaniasis in travelers presenting with compatible symptoms, even after prolonged incubation periods.
  • Emphasizes the need for increased awareness among clinicians regarding diagnostic challenges.
  • Demonstrates the efficacy of amphotericin B lipid complex in treating visceral leishmaniasis.