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[Risk factors for myocardial remodeling at stage II-IV of chronic kidney disease]

T E Rudenko, I M Kutyrina, M Iu Shvetsov

    Terapevticheskii Arkhiv
    |September 25, 2012
    PubMed

    Insights

    Left ventricular hypertrophy (LVH) affects over a third of chronic kidney disease (CKD) patients, linked to both traditional and kidney-specific risk factors. Early detection and management of CKD are crucial for preventing cardiac complications.

    Area of Science:

    • Nephrology
    • Cardiology
    • Internal Medicine

    Context:

    • Chronic kidney disease (CKD) is a growing global health concern.
    • CKD is associated with a significantly increased risk of cardiovascular complications.
    • Left ventricular hypertrophy (LVH) is a common cardiac manifestation in CKD patients.

    Purpose:

    • To determine the prevalence of LVH in patients with stages II-IV CKD.
    • To identify conventional and renal-specific risk factors associated with LVH development in CKD patients.
    • To analyze the different geometric models of LVH in this population.

    Summary:

    • LVH was observed in 37.3% of 83 CKD patients (stages II-IV).
    • LVH development was associated with age, arterial hypertension, hypercholesterolemia, reduced GFR, anemia, and hyperphosphatemia.
    • Eccentric LVH was more common with renal factors, while concentric LVH correlated with higher systolic blood pressure.

    Impact:

    • Highlights the high prevalence of LVH in early to moderate CKD.
    • Underscores the importance of managing both traditional and renal-related risk factors for cardiovascular health in CKD.
    • Informs clinical practice regarding cardiac risk stratification and management in CKD patients.
    Abstract

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